Custom Peptides
Cayman Chemical CIntIrorgon 10mg
A RORɣ agonist (EC50s = <0.5 µM in a reporter assay and TR-FRET assay)
Cayman Chemical Glycyrhza glabra Glabrdn 10mg
A prenylated isoflavonoid that is reported to possess antiviral, antimicrobial, anti-inflammatory, antidiabetic, antiatherogenic, antioxidant, antitumor, and estrogen-like properties
Cayman Chemical aDGalactopyrnosylphenyl Is
Used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate
Cayman Chemical 3-O-methyl-L-DOPAhydrate 10mg
An active metabolite of L-DOPA; inhibits L-DOPA-induced neuroprotection in rat primary mesencephalic dopaminergic neurons at 10 and 100 µM
Cayman Chemical NorgestImate 10mg
A progestin; prodrug form of norelgestromin and levonorgestrel; binds to progestin receptors (mean IC50 = 3.48 nM for rabbit uterine receptors) and is selective for progestin over androgen receptors (mean IC50 = 764 nM for rat prostatic receptors); maintains pregnancy in ovariectomized female rats in a dose-dependent manner; inhibits ovulation in 100% of female rats at 0.5 mg/kg; completely inhibits estrone-induced vaginal cornification in ovariectomized female rats at 2 mg/kg, indicating antiestrogenic activity
Cayman Chemical Temafloxacin 10MG
A fluoroquinolone antibiotic that inhibits DNA topoisomerase inhibitor; broad antimicrobial activity against gram-positive and gram-negative bacteria, such as S. pneumoniae, M. hominis, and anaerobic bacteria, including B. fragilis
Cayman Chemical S-Docosahexaenyl-2-Hyd 10mg
A homolog of DHEA, characterized by the addition of an (S)-β-methyl group at the terminal ethanolamine carbon
Cayman Chemical R-LInoleyl-1-Hydroxy-2 10mg
A homolog of LOEA, characterized by the addition of an (R)-α-methyl group at the methylene carbon adjacent to the amide nitrogen
Cayman Chemical CP 100 356hydrochlorIde 10mg
A P-glycoprotein inhibitor (IC50 = 0.5 µM); selective for P-gp over MRP2 at 15 µM, CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 (IC50s = >50 µM for all), and OATP2B1 (IC50 = ~66 µM) but does inhibit BCRP (IC50 = 1.5 µM); increases the rate of prazosin clearance in rats at 24 mg/kg when administered in combination with prazosin
Cayman Chemical AlexIdInhydrochlorIde 10mg
An alkyl bis(biguanide) antiseptic which kills plaque forming microorganisms; binds to LPS and LTA and inhibits fungal phospholipase B (IC50 ~ 250 nM); inhibits the mitochondrial phosphatase PTPMT1 (IC50 = 1.08 μM, in vitro) and induces apoptosis in cancer cell lines (ED50 = 1.8-2.6 μM)
Cayman Chemical LeukadherIn 1 10mg
An allosteric activator of CD11b/CD18; increases K562 cell adhesion to fibrinogen (EC50 = 4 µM); reduces rolling velocity of leukocytes, decreasing the number of leukocytes recruited to injured tissue; anti-inflammatory in a zebrafish tailfin injury model and a mouse model of nephritis; competitively inhibits YopH (Ki = 1.94 µM) and anthrax lethal factor metalloproteinase (IC50 = 6 µM)
Cayman Chemical 20-hydroxy Ecdyson 10mg
An ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis; used as a tool in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor
Cayman Chemical Seco RapamycInsodIum salt 10mg
A nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration; secreted from cells by P-glycoprotein; poorly activates mTOR but, like rapamycin, inhibits the proteasome
Cayman Chemical Regadenoson 10mg
A selective, short-acting adenosine A2A receptor agonist (Ki = 1.1 nM for pig striatum A2A receptor); used to induce hyperemia, particularly in the context of myocardial perfusion imaging